Patients should also visit their doctor straight away if they experience any signs of thyroid crisis. This is a condition where there is too much thyroid hormone in the body. Symptoms may include a very high temperature, increased heart rate, low blood pressure, heart failure, jaundice, confusion, fits or coma. Other side effects Tablet version: Headache, flushing, raised temperature, sweating, weight loss, tremor, restlessness, excitability, insomnia, benign intracranial hypertension, chest pain, pounding, irregular or fast heartbeat, diarrhoea, vomiting, muscle cramps or weakness, irregular periods, or increased sensitivity to heat. Oral solution: Fast or irregular heart beats, palpitations, rash, itching, puffiness, chest pain, muscle cramps or weakness, headache, restlessness, excitability, flushing, sweating, diarrhoea, vomiting, fever, menstruation problems, high blood pressure in the cranium, tremor, sleeplessness, heat intolerance or excessive weight loss.
The above is not an exhaustive list. Consult the leaflet for more detailed information. Warnings Regular testing It is important to have your thyroid function checked on a regular basis at least once yearly while taking levothyroxine. To arrange this, make an appointment with your GP. Taking it with other medicines Levothyroxine may interact with many different medications, including: epilepsy medicines such as carbamazepine, phenytoin, primidone and barbiturates; sertraline; antacids; medicines containing calcium salts; cimetidine; proton pump inhibitors omeprazole, lansoprazole and pantoprazole ; sucralfate; cholestyramine and colestipol; polystyrene sulphone resin; medicines containing iron; rifampicin; imatinib; beta blockers such as atenolol and sotalol; HRT or contraceptive pills containing oestrogen; androgen containing medicines; corticosteroids; amiodarone; orlistat; anticoagulants; diabetes drugs such as insulin and metformin; tricyclic antidepressants; adrenaline used in severe allergic reactions ; phenylephrine found in cold and flu remedies ; digoxin; anti-inflammatory medicines such as some types of painkillers ; propanolol; or ketamine.
Tell your doctor if you have: an untreated or uncontrolled adrenal gland disorder; a thyroid disorder called thyrotoxicosis; or symptoms of a heart attack chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea , sweating, general ill feeling. Tell your doctor if you have ever had: a thyroid nodule; heart disease, a blood clot, or a blood-clotting disorder; diabetes insulin or oral diabetes medication doses may need to be changed when you start taking levothyroxine ; kidney disease; anemia lack of red blood cells ; osteoporosis , or low bone mineral density; problems with your pituitary gland; or any food or drug allergies. Tell your doctor if you have recently received radiation therapy with iodine such as I-131. If you become pregnant while taking Synthroid, do not stop taking the medicine without your doctor's advice.
Having low thyroid hormone levels during pregnancy could harm both mother and baby. Your dose needs may be different during pregnancy. Tell your doctor if you are breast-feeding. Your dose needs may be different while you are nursing. Do not give Synthroid to a child without medical advice. How should I take Synthroid? Take Synthroid exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Synthroid works best if you take it on an empty stomach, at least 30 to 60 minutes before breakfast. Follow your doctor's dosing instructions and try to take the medicine at the same time each day. Levothyroxine doses are based on weight in children. Your dose needs may change if you gain or lose weight. It may take several weeks before your body starts to respond to levothyroxine.
Keep using this medicine even if you feel well. You may need to use levothyroxine for the rest of your life. You may need frequent medical tests. Tell any doctor, dentist, or surgeon who treats you that you are using Synthroid. Store at room temperature away from moisture and heat.
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